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Learn what drives the simAbs team

Mission

Our mission is to support biopharmaceutical companies in the development and manufacturing of cost-effective therapeutic biologics, and to set a new standard in biopharmaceutical manufacturing technology that enables personalized medicine to become a reality.

Vision

Our vision is to continue to function as a Center of Excellence for the cost-effective biomanufacturing of biologics, to support the evolution of biopharmaceuticals into targeted therapies, and to motivate pharmaceutical companies to develop more innovative products.

We follow three rules in our work:
keep it simple and smart (KISS),
innovate the process,
and enjoy the flow.

As an organization we offer transparency, honest and open communication, and a flexible approach. Most importantly, we provide a personalized approach both to our clients and to the end patient.

Team & Board of Directors

Meet our experienced and diverse team of professionals.

Koen Dierckx, CEO and Co-Founder

Koen Dierckx

CEO, Co-Founder

Koen has over 20 years of experience in R&D, pharmaceutical operations and project management. He has an executive MBA and holds a Master’s degree in Civil Engineering and Biochemistry from the University of Leuven. He has worked for Genzyme, a Sanofi company, where he held several positions in biopharmaceutical operations. He successfully helped the transfer of two production processes and defending the regulatory filing for the EMA and FDA. He is the founder of Pilot Biologix, a biotechnology company that is investing in valorization, technology transfer and scale up of research results in biotechnology. 

Bram Keymolen, Qualified Person and Co-Founder

Bram Keymolen

QP, Co-Founder

Bram has a degree in Industrial Pharmacy and is the Qualified Person within simAbs. He has experience in Quality Management and has supported several projects for GMP licensing of manufacturing facilities. Together with Gunther Coenen, he founded Eye-Tec in 2011. Established as a Visual Inspection consultancy firm, Eye-Tec developed a unique service to healthcare industries by combining experience in both compliance and technical aspects of pharmaceutical manufacturing.

Tom Lokermans, CFO and Co-Founder

Tom Lokermans

CFO, Co-Founder

Tom has a Master’s in Applied Economics from KU Leuven and completed the Executive Masterclass in Corporate Finance from Vlerick Business School. In addition to being our CFO, he is also the CFO of consultancy company Quality by Design, which was selected in 2020 by Deloitte as one of the “Best Managed Companies”.

Joachim Vandeput, Co-Founder

Joachim Vandeput

Co-Founder

Joachim is currently the Team Leader for the Construction Management and Commissioning department within SWECO Industry. He has previous experience as a project manager in the Life Sciences sector for clients such as GlaxoSmithKline, Sanofi, Novartis and JSR Micro. He has in depth experience in various areas of Life Science production facilities, including construction management, commissioning and qualification. Joachim has a Master’s degree in Management from the University of Leuven and a Master’s degree in Chemical Engineering from the University College Group T.

Bart van Acker, Co-Founder

Bart van Acker

Co-Founder

Bart is a bioengineer and the founder of consultancy company Quality by Design. They were founded in 2011 and grew very quickly to become the Belgian reference in consultancy for the Life Sciences industry (pharma, biotechnology, medical devices, cosmetics, healthcare). Today the company employs more than 300 people and is also active in the Netherlands, France, Spain, Mexico and Colombia. In 2019 Bart was elected Flemish Young Entrepreneur of the Year.

Thomas Geuens, Head of research and development

Thomas Geuens

Head of R&D

Thomas obtained his PhD in Biochemistry and Biotechnology at the Flanders Institute for Biotechnology (VIB). There, he was awarded a PhD fellowship from the Research Foundation Flanders (FWO) to unravel phenotypic effects of protein mutations. After a 3-year post-doctoral stay abroad, he joined simAbs as an Upstream Process Development Engineer. In his current role as Head of Research and Development, Thomas coordinates all research and process development activities. Over the years he has built up extensive knowledge in cell line generation, protein expression in mammalian and bacterial cells, protein characterization and bioprocess development.

Elien Wouters, Process Development Engineer

Elien Wouters

Process Development Engineer

Elien obtained her PhD in biomedical sciences at Hasselt University. There, she focused on the role of innate immune cells in autoimmune disorders. After her PhD, she began her career in industry as a project manager at Nelson Labs. As Upstream Process Development Engineer at simAbs, she is involved in cell line engineering and the optimization of upstream processes in shaker flasks and bench-scale bioreactors.

An Vannuland, Head of Quality

An Vannuland

Head of Quality

An holds a PhD in biochemistry and is passionate about cell culture-based products. Previously she worked at TiGenix as a Project Engineer, where she was responsible for the production of the first ATMP product approved by the EMA. In addition to managing all GMP facets within routine production, she also implemented and approved a new GMP production site (including qualification, tech transfer and comparability studies) and worked in close collaboration with the regulatory department. As Quality Responsible she implemented, together with Koen Dierckx (current CEO of simAbs), a protein A production site with a quality system that is meeting pharma customers’ expectations.

Shahbaz Bashir, Process Development Engineer

Shahbaz Bashir

Process Development Engineer

Shahbaz Bashir obtained his doctoral degree (PhD) in Bioscience Engineering at KU Leuven university, Belgium. His doctoral research was focused on the exploration of the immune system of livestock through antibody phage display platform for the isolation of novel antibody binders against viral targets. After his PhD, he started his postdoc in an industry-academia venture at KU Leuven. His postdoc research was mainly focused on the designing and execution of in vivo and in vitro assays to evaluate and validate the efficacy of antiviral drugs. As Process Development Engineer at SimAbs, he is applying different antibody technologies to validate the quality, stability and purity of the antibodies alongside their functionality testing. He is developing and optimizing the antibody drug conjugates and performing systemic evaluation of each component of its design in order to enhance the efficacy of the therapeutic antibodies.

Joppe Hermans

Process Operator

Joppe began his career at Lonza, producing cell-therapy products and expanding his role to include documentation review, site SAP SME, training, and cleanroom supervision. At Medace, Joppe managed projects, guided clients from R&D to GMP production, and provided hands-on cleanroom and GMP support and training. As a GMP production specialist at Exo Biologics, he transferred extracellular vesicle manufacturing in-house, involving cleanroom qualification, documentation authoring, and training. He also prepared and executed APS and engineering runs, securing the site’s GMP license. Currently at simAbs, Joppe ensures seamless technology transfer, performs cleanroom production, manages stock and equipment, and leverages his GMP expertise to support clients.

Marijn Bollema

QC Engineer

Marijn obtained a bachelor’s degree in biochemistry at Hogeschool Zuyd in Heerlen. He began his career at PharmaCell in Maastricht joining as a Biotech Associate performing aseptic fillings in a grade B environment. When an opportunity arose, Marijn joints the QC team setting up the QC department (including cellular assays using e.g., flow-cytometry, safety testing, stability testing, tech transfer projects and helping within R&D projects). As GMP became a second nature he decided to broaden his wings and join MSD in Oss within the microbiological validation group. But the urge to work for a start-up company grew and he started working for CiMaas in Maastricht as a process development & research associate combined with a QA function, implementing a QMS system which was well received by the IgJ. As a QC Lab engineer at SimAbs, he is helping to set up the QC lab and tech transfer activities with great enthusiasm were all his previous experience help him using his full potential.

Amelie Verboven

QC Engineer

Amelie obtained her Master’s degree in Drug Development (Pharmaceutical Sciences) at KU Leuven University. She began her professional career as a Life Sciences Consultant, working as a Laboratory LC Analyst at Johnson & Johnson, where she developed expertise in GMP guidelines, laboratory analyses, and (high-priority) protein projects. At SimAbs, she is part of the Quality team as a QC Engineer, applying her quality and practical expertise.

Kenneth Segers

Process Development Engineer

Kenneth obtained his PhD in Biochemistry at the Cardiovascular Research Institute Maastricht (CARIM). During his PhD project, he combined biochemistry and molecular biology techniques with structural bioinformatics to investigate the molecular structure and function of human blood coagulation factor V. After his PhD, he started a post-doc at the Rega Institute for Medical Research (KU Leuven). There, he worked on the development of (high-throughput) screening assays to identify antibacterials targeting bacterial protein secretion. During a second post-doc at Johnson & Johnson, he developed a cell-free expression system for membrane proteins and other types of proteins that are difficult to produce in cell-based expression systems.Previously, Kenneth worked at Sanofi as a downstream process engineer where he supported the tech transfer of various therapeutic mAbs. In his current role as process development engineer, he is engaged in the further development of simAbs’ continuous manufacturing platform for the production of biotherapeutics.

Dimitri Stevens

Project Manager Tech transfer

Dimi holds a Master’s degree in Biology with a specialization in Biochemistry from the University of Antwerp. With over 20 years of experience in GMP and cell culture-based products, he has held key positions at TiGenix, Lonza, and ExoBiologics, focusing on production, process development, and tech transfer. Currently, as a Project Manager, Dimi manages the tech transfer of new projects.

Dany Fluchard

QC Expert

Dany holds a master’s degree in chemistry from the University of Liège and has extensive experience in biomolecule analysis and laboratory management in GMP environments. He has a proven track record in leading analytical teams, ensuring compliance with regulatory standards, and driving efficiency in laboratory operations. His expertise spans a wide range of analytical techniques and quality control processes, making him a valuable asset in the biopharmaceutical and life sciences industries. As a QC Expert, I am ensuring the compliance with current manufacturing standards and regulations, assay transfers and their qualification/validation at simAbs.

Dorien Ceusters

Manufacturing Associate

Dorien holds a Master’s degree in Biomedical Sciences from KU Leuven. She previously worked as an EQA Scheme Coordinator at KU Leuven, ensuring the maintenance and improvement of the Quality Management System.  At simAbs, she supports GMP production runs, identifies process deviations, initiates corrective actions, and ensures strict compliance with clinical manufacturing guidelines. Her expertise in quality assurance and passion for process optimization make her a valuable asset to the team.

We are located in BioVille, Belgium

Opened in 2010,  BioVille is a hub for start-ups and growing companies in the life sciences. Their goal is to assist starting and growing health & care companies by offering them flexible spaces and customized support services. In addition, BioVille was part of the Limburg ambition to make life sciences one of the key sectors in the region. Currently, more than 30 companies and more than 120 colleagues are based at BioVille. The focus is mainly on health & care, biotech, medtech and digital health.

Careers

SimAbs currently has no open positions.
Stay tuned for future opportunities, and follow us on LinkedIn.

Quality Control Lab Engineer

We are SIMABS SIMABS is a biotechnology venture that provides cost effective therapeutic monoclonal antibodies to biopharmaceutical companies. We are hiring a Process Operator who has a startup vibe to

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simAbs is a start-up biotechnology venture that is developing a new bio-manufacturing platform to provide cost-effective therapeutic biologics at small scale to biopharmaceutical companies. This technology will enable personalized medicine to become an affordable reality.

Our values are: keep it simple & smart (KISS), innovate the process and last but not least, enjoy the flow.

Be part of our mission and set the new standard in biopharmaceutical manufacturing technology that enables personalized medicine to become a reality.

Location
Diepenbeek, BE

Job content
As our Automation Engineer, you are passionate in building mechanical systems and automating them. You are responsible for the system design and engineering in our plant to develop an innovative and cost-effective production platform for mammalian single-use cell culture and purification. You apply technical knowledge by providing automation solutions for the life science process equipment involved: work process, unit operations, operating conditions, or process technology improvements.

Responsibilities

  • Procure, install, test, calibrate and maintain operating equipment in order to develop a robust and cost-efficient production platform, in close collaboration with our process development engineers
  • Develop, program and configure automation structure to ensure a smooth and reliable process
  • Lead technical troubleshooting and implement actions to avoid recurrence
  • Ensure data integrity on all equipment
  • Responsible for equipment software, network, accounts, as well as data processing
  • Identify technical issues and implement creative solutions
  • Ensure high quality documentation
  • Follow up on the latest technical insights in your field of expertise
  • Technical assistance for our USP and DSP Engineer
  • Engage in a broad range of activities in order to grow simAbs into a strong and reliable partner for future clients

Education
Master of science in an industrial sciences (automation, electronics, electromechanics, biochemistry, etc.) or

Degree in bioengineering, combined with a strong technical and automation background

Competences

Technical skills:

  • Broad technical knowledge of process equipment and operating equipment
  • Siemens PCS7 and/or DeltaV
  • PLC
  • 21cfr part11
  • Able to read and use electrical and technical drawings
  • Experience in life science industry
  • Experience with single-use process equipment

Soft skills:

  • Entrepreneurial with strong intrinsic motivation and ownership
  • Hands-on, well organized and result-oriented team player
  • Enjoying the start-up flow of our organization
  • Strong and honest communicator
  • Flexible both in content and time

Interested?
Do you want to share our passion in enabling  personalized medicine to become an affordable reality?

Apply by sending your cv to jobs@simabs.com